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The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

Abstract Backgrounds The aberrant activation of complement system is critically involved in lupus nephropathy. Recent study showed complement C3 inhibitor was effective in the treatment of lupus nephropathy. In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the...

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Autores principales: Yu Shi, Wen Yao, Li Sun, Guomin Li, Haimei Liu, Peipei Ding, Weiguo Hu, Hong Xu
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2019-11-01
Colección:BMC Nephrology
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Acceso en línea:http://link.springer.com/article/10.1186/s12882-019-1599-0
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