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The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

BACKGROUNDS: The aberrant activation of complement system is critically involved in lupus nephropathy. Recent study showed complement C3 inhibitor was effective in the treatment of lupus nephropathy. In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the treatme...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Shi, Yu, Yao, Wen, Sun, Li, Li, Guomin, Liu, Haimei, Ding, Peipei, Hu, Weiguo, Xu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873683/
https://ncbi.nlm.nih.gov/pubmed/31752725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1599-0
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