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Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8(+) T Cell Response
In this communication, we demonstrate that galectin (Gal)-9 acts to constrain CD8(+) T cell immunity to Herpes Simplex Virus (HSV) infection. In support of this, we show that animals unable to produce Gal-9, because of gene knockout, develop acute and memory responses to HSV that are of greater magn...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865527/ https://ncbi.nlm.nih.gov/pubmed/20463811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000882 |
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