Multi-scale model of drug induced adaptive resistance of Gram-negative bacteria to polymyxin B

Por Krzyzanski, Wojciech, Rao, Gauri G.
Publicado no PLoS One (2017)

Mechanism‐Based Disease Progression Model Describing Host‐Pathogen Interactions During the Pathogenesis of Acinetobacter baumannii Pneumonia

Por Diep, John K., Russo, Thomas A., Rao, Gauri G.
Publicado no CPT Pharmacometrics Syst Pharmacol (2018)

Evaluation of Activity and Emergence of Resistance of Polymyxin B and ZTI-01 (Fosfomycin for Injection) against KPC-Producing Klebsiella pneumoniae

Por Diep, John K., Sharma, Rajnikant, Ellis-Grosse, Evelyn J., Abboud, Cely S., Rao, Gauri G.
Publicado no Antimicrob Agents Chemother (2018)

Triple combination antibiotic therapy for carbapenemase-producing Klebsiella pneumoniae: a systematic review

Por Jacobs, David M., Safir, M. Courtney, Huang, Dennis, Minhaj, Faisal, Parker, Adam, Rao, Gauri G.
Publicado no Ann Clin Microbiol Antimicrob (2017)

Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm

Por Lakota, Elizabeth A., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Kaye, Keith S., Rao, Gauri G., Forrest, Alan
Publicado no Antimicrob Agents Chemother (2018)

Polymyxin B in Combination with Rifampin and Meropenem against Polymyxin B-Resistant KPC-Producing Klebsiella pneumoniae

Por Diep, John K., Jacobs, David M., Sharma, Rajnikant, Covelli, Jenna, Bowers, Dana R., Russo, Thomas A., Rao, Gauri G.
Publicado no Antimicrob Agents Chemother (2017)

Polymyxin B in combination with meropenem against carbapenemase-producing Klebsiella pneumoniae: pharmacodynamics and morphological changes

Por Sharma, Rajnikant, Patel, Saloni, Abboud, Cely, Diep, John, Ly, Neang S., Pogue, Jason M., Kaye, Keith S., Li, Jian, Rao, Gauri G.
Publicado no Int J Antimicrob Agents (2016)

Critical Need for Clarity in Polymyxin B Dosing

Por Onufrak, Nikolas J., Rao, Gauri G., Forrest, Alan, Pogue, Jason M., Scheetz, Marc H., Nation, Roger L., Li, Jian, Kaye, Keith S.
Publicado no Antimicrob Agents Chemother (2017)

Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii

Por Rao, Gauri G., Ly, Neang S., Diep, John, Forrest, Alan, Bulitta, Jürgen B., Holden, Patricia N., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Publicado no Int J Antimicrob Agents (2016)

Optimization of Polymyxin B in Combination with Doripenem To Combat Mutator Pseudomonas aeruginosa

Por Ly, Neang S., Bulman, Zackery P., Bulitta, Jürgen B., Baron, Christopher, Rao, Gauri G., Holden, Patricia N., Li, Jian, Sutton, Mark D., Tsuji, Brian T.
Publicado no Antimicrob Agents Chemother (2016)

In Vitro Assessment of Combined Polymyxin B and Minocycline Therapy against Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae

Por Huang, Dennis, Yu, Brenda, Diep, John K., Sharma, Rajnikant, Dudley, Michael, Monteiro, Jussimara, Kaye, Keith S., Pogue, Jason M., Abboud, Cely Saad, Rao, Gauri G.
Publicado no Antimicrob Agents Chemother (2017)

Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance

Por Ly, Neang S., Bulitta, Jürgen B., Rao, Gauri G., Landersdorfer, Cornelia B., Holden, Patricia N., Forrest, Alan, Bergen, Phillip J., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Publicado no J Antimicrob Chemother (2015)

New Dosing Strategies for an Old Antibiotic: Pharmacodynamics of Front-Loaded Regimens of Colistin at Simulated Pharmacokinetics in Patients with Kidney or Liver Disease

Por Rao, Gauri G., Ly, Neang S., Haas, Curtis E., Garonzik, Samira, Forrest, Alan, Bulitta, Jurgen B., Kelchlin, Pamela A., Holden, Patricia N., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Publicado em 2014

Paradoxical Effect of Polymyxin B: High Drug Exposure Amplifies Resistance in Acinetobacter baumannii

Por Tsuji, Brian T., Landersdorfer, Cornelia B., Lenhard, Justin R., Cheah, Soon-Ee, Thamlikitkul, Visanu, Rao, Gauri G., Holden, Patricia N., Forrest, Alan, Bulitta, Jürgen B., Nation, Roger L., Li, Jian
Publicado no Antimicrob Agents Chemother (2016)

Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

Por Rao, Gauri G., Ly, Neang S., Bulitta, Jürgen B., Soon, Rachel L., San Roman, Marie D., Holden, Patricia N., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Forrest, Alan, Tsuji, Brian T.
Publicado no J Antimicrob Chemother (2016)

Polymyxin B in Combination with Enrofloxacin Exerts Synergistic Killing against Extensively Drug-Resistant Pseudomonas aeruginosa

Por Lin, Yu-Wei, Yu, Heidi H., Zhao, Jinxin, Han, Mei-Ling, Zhu, Yan, Akter, Jesmin, Wickremasinghe, Hasini, Walpola, Hasini, Wirth, Veronika, Rao, Gauri G., Forrest, Alan, Velkov, Tony, Li, Jian
Publicado no Antimicrob Agents Chemother (2018)

Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact

Por Gonzalez, Daniel, Rao, Gauri G., Bailey, Stacy C., Brouwer, Kim L.R., Cao, Yanguang, Crona, Daniel J., Kashuba, Angela D.M., Lee, Craig R., Morbitzer, Kathryn, Patterson, J. Herbert, Wiltshire, Tim, Easter, Jon, Savage, Scott W., Powell, J. Robert
Publicado no Clin Transl Sci (2017)