Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

OBJECTIVES: Polymyxin B is being increasingly utilized as a last resort against resistant Gram-negative bacteria. We examined the pharmacodynamics of novel dosing strategies for polymyxin B combinations to maximize efficacy and minimize the emergence of resistance and drug exposure against Acinetoba...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Antimicrob Chemother
Prif Awduron: Rao, Gauri G., Ly, Neang S., Bulitta, Jürgen B., Soon, Rachel L., San Roman, Marie D., Holden, Patricia N., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Forrest, Alan, Tsuji, Brian T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079300/
https://ncbi.nlm.nih.gov/pubmed/27494922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw293
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