Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

OBJECTIVES: Polymyxin B is being increasingly utilized as a last resort against resistant Gram-negative bacteria. We examined the pharmacodynamics of novel dosing strategies for polymyxin B combinations to maximize efficacy and minimize the emergence of resistance and drug exposure against Acinetoba...

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Библиографические подробности
Опубликовано в: :J Antimicrob Chemother
Главные авторы: Rao, Gauri G., Ly, Neang S., Bulitta, Jürgen B., Soon, Rachel L., San Roman, Marie D., Holden, Patricia N., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Forrest, Alan, Tsuji, Brian T.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079300/
https://ncbi.nlm.nih.gov/pubmed/27494922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw293
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