Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

OBJECTIVES: Polymyxin B is being increasingly utilized as a last resort against resistant Gram-negative bacteria. We examined the pharmacodynamics of novel dosing strategies for polymyxin B combinations to maximize efficacy and minimize the emergence of resistance and drug exposure against Acinetoba...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Antimicrob Chemother
Päätekijät: Rao, Gauri G., Ly, Neang S., Bulitta, Jürgen B., Soon, Rachel L., San Roman, Marie D., Holden, Patricia N., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Forrest, Alan, Tsuji, Brian T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079300/
https://ncbi.nlm.nih.gov/pubmed/27494922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw293
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