Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii

The prevalence of heteroresistant Acinetobacter baumannii is increasing. Infections due to these resistant pathogens pose a global treatment challenge. Here, the pharmacodynamic activities of polymyxin B (PMB) (2–20 mg/L) and tigecycline (0.15–4 mg/L) were evaluated as monotherapy and in combination...

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Veröffentlicht in:Int J Antimicrob Agents
Hauptverfasser: Rao, Gauri G., Ly, Neang S., Diep, John, Forrest, Alan, Bulitta, Jürgen B., Holden, Patricia N., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256686/
https://ncbi.nlm.nih.gov/pubmed/27449542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2016.06.006
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