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In Vitro Pharmacodynamics of Polymyxin B and Tigecycline Alone and in Combination against Carbapenem-Resistant Acinetobacter baumannii

Carbapenem-resistant Acinetobacter baumannii is increasing in prevalence. Polymyxin B and tigecycline are among the most active antibiotics used against this pathogen in vitro. Past in vitro studies, however, neglected the importance of simulating exposures observed in humans to determine their anti...

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Détails bibliographiques
Auteurs principaux: Hagihara, Mao, Housman, Seth T., Nicolau, David P., Kuti, Joseph L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910875/
https://ncbi.nlm.nih.gov/pubmed/24277022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01624-13
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