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In Vitro Pharmacodynamics of Polymyxin B and Tigecycline Alone and in Combination against Carbapenem-Resistant Acinetobacter baumannii

Carbapenem-resistant Acinetobacter baumannii is increasing in prevalence. Polymyxin B and tigecycline are among the most active antibiotics used against this pathogen in vitro. Past in vitro studies, however, neglected the importance of simulating exposures observed in humans to determine their anti...

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Autors principals: Hagihara, Mao, Housman, Seth T., Nicolau, David P., Kuti, Joseph L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910875/
https://ncbi.nlm.nih.gov/pubmed/24277022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01624-13
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