In Vitro Assessment of Combined Polymyxin B and Minocycline Therapy against Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae

The multidrug resistance profiles of Klebsiella pneumoniae carbapenemase (KPC) producers have led to increased clinical polymyxin use. Combination therapy with polymyxins may improve treatment outcomes, but it is uncertain which combinations are most effective. Clinical successes with intravenous mi...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Huang, Dennis, Yu, Brenda, Diep, John K., Sharma, Rajnikant, Dudley, Michael, Monteiro, Jussimara, Kaye, Keith S., Pogue, Jason M., Abboud, Cely Saad, Rao, Gauri G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487624/
https://ncbi.nlm.nih.gov/pubmed/28438930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00073-17
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