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Polymyxin B in Combination with Rifampin and Meropenem against Polymyxin B-Resistant KPC-Producing Klebsiella pneumoniae

Safe and effective therapies are urgently needed to treat polymyxin-resistant KPC-producing Klebsiella pneumoniae infections and suppress the emergence of resistance. We investigated the pharmacodynamics of polymyxin B, rifampin, and meropenem alone and as polymyxin B-based double and triple combina...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Diep, John K., Jacobs, David M., Sharma, Rajnikant, Covelli, Jenna, Bowers, Dana R., Russo, Thomas A., Rao, Gauri G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278701/
https://ncbi.nlm.nih.gov/pubmed/27872078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02121-16
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