In Vitro Assessment of Combined Polymyxin B and Minocycline Therapy against Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae

The multidrug resistance profiles of Klebsiella pneumoniae carbapenemase (KPC) producers have led to increased clinical polymyxin use. Combination therapy with polymyxins may improve treatment outcomes, but it is uncertain which combinations are most effective. Clinical successes with intravenous mi...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Huang, Dennis, Yu, Brenda, Diep, John K., Sharma, Rajnikant, Dudley, Michael, Monteiro, Jussimara, Kaye, Keith S., Pogue, Jason M., Abboud, Cely Saad, Rao, Gauri G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487624/
https://ncbi.nlm.nih.gov/pubmed/28438930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00073-17
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