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Optimization of Polymyxin B in Combination with Doripenem To Combat Mutator Pseudomonas aeruginosa
Development of spontaneous mutations in Pseudomonas aeruginosa has been associated with antibiotic failure, leading to high rates of morbidity and mortality. Our objective was to evaluate the pharmacodynamics of polymyxin B combinations against rapidly evolving P. aeruginosa mutator strains and to c...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862466/ https://ncbi.nlm.nih.gov/pubmed/26926641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02377-15 |
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