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Impact of Two-Component Regulatory Systems PhoP-PhoQ and PmrA-PmrB on Colistin Pharmacodynamics in Pseudomonas aeruginosa

The in vitro pharmacodynamics of colistin against Pseudomonas aeruginosa PAO1 wild-type and isogenic knockout strains of phoP and pmrA were evaluated. Colistin killing at subinhibitory concentrations was greater against the phoP and pmrA mutants than the wild type within the first 8 h: the concentra...

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Bibliografske podrobnosti
Main Authors: Ly, Neang S., Yang, Jenny, Bulitta, Jurgen B., Tsuji, Brian T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370801/
https://ncbi.nlm.nih.gov/pubmed/22470116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06380-11
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