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Identification of Novel phoP-phoQ Regulated Genes that Contribute to Polymyxin B Tolerance in Pseudomonas aeruginosa

Polymyxin B and E (colistin) are the last resorts to treat multidrug-resistant Gram-negative pathogens. Pseudomonas aeruginosa is intrinsically resistant to a variety of antibiotics. The PhoP-PhoQ two-component regulatory system contributes to the resistance to polymyxins by regulating an arnBCADTEF...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Yang, Baopeng, Liu, Chang, Pan, Xiaolei, Fu, Weixin, Fan, Zheng, Jin, Yongxin, Bai, Fang, Cheng, Zhihui, Wu, Weihui
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916210/
https://ncbi.nlm.nih.gov/pubmed/33572426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9020344
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