Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression

Bằng Rangasamy, Tirumalai, Misra, Vikas, Zhen, Lijie, Tankersley, Clarke G., Tuder, Rubin M., Biswal, Shyam
Được phát hành 2009

MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells

Bằng Solleti, Siva Kumar, Bhattacharya, Soumyaroop, Ahmad, Ausaf, Wang, Qian, Mereness, Jared, Rangasamy, Tirumalai, Mariani, Thomas J.
Xuất bản năm Sci Rep (2017)

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

Bằng Thimmulappa, Rajesh K., Lee, Hannah, Rangasamy, Tirumalai, Reddy, Sekhar P., Yamamoto, Masayuki, Kensler, Thomas W., Biswal, Shyam
Được phát hành 2006

Nuclear Erythroid 2 p45-Related Factor 2 Inhibits the Maturation of Murine Dendritic Cells by Ragweed Extract

Bằng Rangasamy, Tirumalai, Williams, Marc A., Bauer, Stephen, Trush, Michael A., Emo, Jason, Georas, Steve N., Biswal, Shyam
Được phát hành 2010

Lpa2 is a negative regulator of dendritic cell activation and murine models of allergic lung inflammation

Bằng Emo, Jason, Meednu, Nida, Chapman, Timothy J., Rezaee, Fariba, Balys, Marlene, Randall, Troy, Rangasamy, Tirumalai, Georas, Steve N.
Được phát hành 2012

Impaired Lung Homeostasis in Neonatal Mice Exposed to Cigarette Smoke

Bằng McGrath-Morrow, Sharon, Rangasamy, Tirumalai, Cho, Cecilia, Sussan, Thomas, Neptune, Enid, Wise, Robert, Tuder, Rubin M., Biswal, Shyam
Được phát hành 2008

Glutathione Peroxidase 2, the Major Cigarette Smoke–Inducible Isoform of GPX in Lungs, Is Regulated by Nrf2

Bằng Singh, Anju, Rangasamy, Tirumalai, Thimmulappa, Rajesh K., Lee, Hannah, Osburn, William O., Brigelius-Flohé, Regina, Kensler, Thomas W., Yamamoto, Masayuki, Biswal, Shyam
Được phát hành 2006

T-Cell Activation under Hypoxic Conditions Enhances IFN-γ Secretion

Bằng Roman, Jessica, Rangasamy, Tirumalai, Guo, Jia, Sugunan, Siva, Meednu, Nida, Packirisamy, Gopinath, Shimoda, Larissa A., Golding, Amit, Semenza, Gregg, Georas, Steve N.
Được phát hành 2010

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

Bằng Rangasamy, Tirumalai, Cho, Chung Y., Thimmulappa, Rajesh K., Zhen, Lijie, Srisuma, Sorachai S., Kensler, Thomas W., Yamamoto, Masayuki, Petrache, Irina, Tuder, Rubin M., Biswal, Shyam
Được phát hành 2004

Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter

Bằng Williams, Marc A., Rangasamy, Tirumalai, Bauer, Stephen M., Killedar, Smruti, Karp, Matthew, Kensler, Thomas W., Yamamoto, Masayuki, Breysse, Patrick, Biswal, Shyam, Georas, Steve N.
Được phát hành 2008

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

Bằng Rangasamy, Tirumalai, Guo, Jia, Mitzner, Wayne A., Roman, Jessica, Singh, Anju, Fryer, Allison D., Yamamoto, Masayuki, Kensler, Thomas W., Tuder, Rubin M., Georas, Steve N., Biswal, Shyam
Được phát hành 2005

Cell stiffness, contractile stress and the role of extracellular matrix

Bằng An, Steven S., Kim, Jina, Ahn, Kwangmi, Trepat, Xavier, Drake, Kenneth J., Kumar, Sarvesh, Ling, Guoyu, Purington, Carolyn, Rangasamy, Tirumalai, Kensler, Thomas W., Mitzner, Wayne, Fredberg, Jeffrey J., Biswal, Shyam
Được phát hành 2009

Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice

Bằng Solleti, Siva Kumar, Simon, Dawn M., Srisuma, Sorachai, Arikan, Meltem C., Bhattacharya, Soumyaroop, Rangasamy, Tirumalai, Bijli, Kaiser M., Rahman, Arshad, Crossno, Joseph T., Shapiro, Steven D., Mariani, Thomas J.
Xuất bản năm Am J Physiol Lung Cell Mol Physiol (2015)

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Bằng Sussan, Thomas E., Rangasamy, Tirumalai, Blake, David J., Malhotra, Deepti, El-Haddad, Hazim, Bedja, Djahida, Yates, Melinda S., Kombairaju, Ponvijay, Yamamoto, Masayuki, Liby, Karen T., Sporn, Michael B., Gabrielson, Kathleen L., Champion, Hunter C., Tuder, Rubin M., Kensler, Thomas W., Biswal, Shyam
Được phát hành 2009

Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke – induced pulmonary injury and emphysema

Bằng Yoshida, Toshinori, Mett, Igor, Bhunia, Anil K., Bowman, Joel, Perez, Mario, Zhang, Li, Gandjeva, Aneta, Zhen, Lijie, Chukwueke, Ugonma, Mao, Thianzi, Richter, Amy, Brown, Emile, Ashush, Hagit, Notkin, Natalie, Gelfand, Anna, Thimmulappa, Rajesh K, Rangasamy, Tirumalai, Sussman, Thomas, Cosgrove, Gregory, Mouded, Majd, Shapiro, Steven D, Petrache, Irina, Biswal, Shyam, Feinstein, Elena, Tuder, Rubin M.
Được phát hành 2010