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T-Cell Activation under Hypoxic Conditions Enhances IFN-γ Secretion

Secondary lymphoid organs and peripheral tissues are characterized by hypoxic microenvironments, both in the steady state and during inflammation. Although hypoxia regulates T-cell metabolism and survival, very little is known about whether or how hypoxia influences T-cell activation. We stimulated...

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Detalhes bibliográficos
Main Authors: Roman, Jessica, Rangasamy, Tirumalai, Guo, Jia, Sugunan, Siva, Meednu, Nida, Packirisamy, Gopinath, Shimoda, Larissa A., Golding, Amit, Semenza, Gregg, Georas, Steve N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809218/
https://ncbi.nlm.nih.gov/pubmed/19372249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0139OC
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