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Enhanced Interferon-γ Gene Expression in T Cells and Reduced Ovalbumin-Dependent Lung Eosinophilia in Hypoxia-Inducible Factor-1-α-Deficient Mice

BACKGROUND: There is growing evidence that hypoxia-inducible transcription factors are involved in the pathophysiology of asthma. Hypoxia-inducible factor-1α (HIF-1α) in particular controls the expression of many hypoxia regulated genes, but whether HIF-1α directly contributes to allergen-driven imm...

詳細記述

保存先:
書誌詳細
主要な著者: Guo, Jia, Lu, Wenju, Shimoda, Larissa A., Semenza, Gregg L., Georas, Steve N.
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824623/
https://ncbi.nlm.nih.gov/pubmed/19127065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000189191
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