Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

Although inflammation and protease/antiprotease imbalance have been postulated to be critical in cigarette smoke–induced (CS-induced) emphysema, oxidative stress has been suspected to play an important role in chronic obstructive pulmonary diseases. Susceptibility of the lung to oxidative injury, su...

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Autores principales: Rangasamy, Tirumalai, Cho, Chung Y., Thimmulappa, Rajesh K., Zhen, Lijie, Srisuma, Sorachai S., Kensler, Thomas W., Yamamoto, Masayuki, Petrache, Irina, Tuder, Rubin M., Biswal, Shyam
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC524225/
https://ncbi.nlm.nih.gov/pubmed/15520857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421146
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