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Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice
Although inflammation and protease/antiprotease imbalance have been postulated to be critical in cigarette smoke–induced (CS-induced) emphysema, oxidative stress has been suspected to play an important role in chronic obstructive pulmonary diseases. Susceptibility of the lung to oxidative injury, su...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524225/ https://ncbi.nlm.nih.gov/pubmed/15520857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421146 |
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