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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
Host genetic factors that regulate innate immunity determine susceptibility to sepsis. Disruption of nuclear factor-erythroid 2–related factor 2 (Nrf2), a basic leucine zipper transcription factor that regulates redox balance and stress response, dramatically increased the mortality of mice in respo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421348/ https://ncbi.nlm.nih.gov/pubmed/16585964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25790 |
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