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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

Host genetic factors that regulate innate immunity determine susceptibility to sepsis. Disruption of nuclear factor-erythroid 2–related factor 2 (Nrf2), a basic leucine zipper transcription factor that regulates redox balance and stress response, dramatically increased the mortality of mice in respo...

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Bibliografische gegevens
Hoofdauteurs: Thimmulappa, Rajesh K., Lee, Hannah, Rangasamy, Tirumalai, Reddy, Sekhar P., Yamamoto, Masayuki, Kensler, Thomas W., Biswal, Shyam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421348/
https://ncbi.nlm.nih.gov/pubmed/16585964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25790
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