Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter

Oxidative stress is important in dendritic cell (DC) activation. Environmental particulate matter (PM) directs pro-oxidant activities that may alter DC function. Nuclear erythroid 2 p45-related factor 2 (Nrf2) is a redox-sensitive transcription factor that regulates expression of antioxidant and det...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams, Marc A., Rangasamy, Tirumalai, Bauer, Stephen M., Killedar, Smruti, Karp, Matthew, Kensler, Thomas W., Yamamoto, Masayuki, Breysse, Patrick, Biswal, Shyam, Georas, Steve N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086516/
https://ncbi.nlm.nih.gov/pubmed/18802057
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