Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres

od da Silva Lopes, Katharina, Pietas, Agnieszka, Radke, Michael H., Gotthardt, Michael
Izdano 2011

Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy

od Hinze, Florian, Dieterich, Christoph, Radke, Michael H., Granzier, Henk, Gotthardt, Michael
Izdano u J Mol Med (Berl) (2016)

Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics

od Elhamine, Fatiha, Radke, Michael H., Pfitzer, Gabriele, Granzier, Henk, Gotthardt, Michael, Stehle, Robert
Izdano 2014

Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes.

od Radke, Michael H., Polack, Christopher, Methawasin, Mei, Fink, Claudia, Granzier, Henk L., Gotthardt, Michael
Izdano u Circulation (2019)

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy

od Radke, Michael H., Peng, Jun, Wu, Yiming, McNabb, Mark, Nelson, O. Lynne, Granzier, Henk, Gotthardt, Michael
Izdano 2007

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

od Liss, Martin, Radke, Michael H., Eckhard, Jamina, Neuenschwander, Martin, Dauksaite, Vita, von Kries, Jens-Peter, Gotthardt, Michael
Izdano u PLoS One (2018)

Titin Based Viscosity in Ventricular Physiology: An Integrative Investigation of PEVK-Actin Interactions

od Chung, Charles S, Methawasin, Methajit, Nelson, O Lynne, Radke, Michael H, Hidalgo, Carlos G, Gotthardt, Michael, Granzier, Henk L
Izdano 2011

The tight junction protein CAR regulates cardiac conduction and cell–cell communication

od Lisewski, Ulrike, Shi, Yu, Wrackmeyer, Uta, Fischer, Robert, Chen, Chen, Schirdewan, Alexander, Jüttner, Rene, Rathjen, Fritz, Poller, Wolfgang, Radke, Michael H., Gotthardt, Michael
Izdano 2008

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

od Rudolph, Franziska, Fink, Claudia, Hüttemeister, Judith, Kirchner, Marieluise, Radke, Michael H., Lopez Carballo, Jacobo, Wagner, Eva, Kohl, Tobias, Lehnart, Stephan E., Mertins, Philipp, Gotthardt, Michael
Izdano u Nat Commun (2020)

Truncation of titin’s elastic PEVK region leads to cardiomyopathy with diastolic dysfunction

od Granzier, Henk L., Radke, Michael H., Peng, Jun, Westermann, Dirk, Nelson, O. Lynne, Rost, Katharina, King, Nicholas M.P., Yu, Qianli, Tschöpe, Carsten, McNabb, Mark, Larson, Douglas F., Labeit, Siegfried, Gotthardt, Michael
Izdano 2009

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing

od Maatz, Henrike, Jens, Marvin, Liss, Martin, Schafer, Sebastian, Heinig, Matthias, Kirchner, Marieluise, Adami, Eleonora, Rintisch, Carola, Dauksaite, Vita, Radke, Michael H., Selbach, Matthias, Barton, Paul J.R., Cook, Stuart A., Rajewsky, Nikolaus, Gotthardt, Michael, Landthaler, Markus, Hubner, Norbert
Izdano 2014

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

od Guo, Wei, Schafer, Sebastian, Greaser, Marion L., Radke, Michael H., Liss, Martin, Govindarajan, Thirupugal, Maatz, Henrike, Schulz, Herbert, Li, Shijun, Parrish, Amanda M., Dauksaite, Vita, Vakeel, Padmanabhan, Klaassen, Sabine, Gerull, Brenda, Thierfelder, Ludwig, Regitz-Zagrosek, Vera, Hacker, Timothy A., Saupe, Kurt W., Dec, G. William, Ellinor, Patrick T., MacRae, Calum A., Spallek, Bastian, Fischer, Robert, Perrot, Andreas, Özcelik, Cemil, Saar, Kathrin, Hubner, Norbert, Gotthardt, Michael
Izdano 2012