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Titin Based Viscosity in Ventricular Physiology: An Integrative Investigation of PEVK-Actin Interactions
Viscosity is proposed to modulate diastolic function, but only limited understanding of the source(s) of viscosity exists. In-vitro experiments have shown that the proline-glutamic acid-valine-lysine (PEVK) rich element of titin interacts with actin, causing a viscous force in the sarcomere. It is u...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150406/ https://ncbi.nlm.nih.gov/pubmed/21708170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.06.006 |
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