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The Effects of PKCα Phosphorylation on the Extensibility of Titin’s PEVK Element
Posttranslational modifications, along with isoform splicing, of titin determine the passive tension development of stretched sarcomeres. It was recently shown that PKCα phosphorylates two highly-conserved residues (S26 and S170) of the PEVK region in cardiac titin, resulting in passive tension incr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856808/ https://ncbi.nlm.nih.gov/pubmed/20149875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.02.002 |
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