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Single Molecule Force Spectroscopy of the Cardiac Titin N2B Element: EFFECTS OF THE MOLECULAR CHAPERONE αB-CRYSTALLIN WITH DISEASE-CAUSING MUTATIONS
The small heat shock protein αB-crystallin interacts with N2B-Us, a large unique sequence found in the N2B element of cardiac titin. Using single molecule force spectroscopy, we studied the effect of αB-crystallin on the N2B-Us and its flanking Ig-like domains. Ig domains from the proximal tandem Ig...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679491/ https://ncbi.nlm.nih.gov/pubmed/19282282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809743200 |
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