Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Proximity proteomics has greatly advanced the analysis of native protein complexes and subcellular structures in culture, but has not been amenable to study development and disease in vivo. Here, we have generated a knock-in mouse with the biotin ligase (BioID) inserted at titin’s Z-disc region to i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rudolph, Franziska, Fink, Claudia, Hüttemeister, Judith, Kirchner, Marieluise, Radke, Michael H., Lopez Carballo, Jacobo, Wagner, Eva, Kohl, Tobias, Lehnart, Stephan E., Mertins, Philipp, Gotthardt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305127/
https://ncbi.nlm.nih.gov/pubmed/32561764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16929-8
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