UPR-inducible micro-RNAs contribute to stressful situations

Por Chitnis, Nilesh, Pytel, Dariusz, Diehl, J. Alan
Publicado em 2013

Tumor progression and the Different Faces of the PERK kinase

Por Pytel, Dariusz, Majsterek, Ireneusz, Diehl, J. Alan
Publicado no Oncogene (2015)

Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer’s Disease

Por Rozpędek, Wioletta, Markiewicz, Łukasz, Diehl, J. Alan, Pytel, Dariusz, Majsterek, Ireneusz
Publicado no Curr Med Chem (2015)

Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1β as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients

Por Markiewicz, Lukasz, Pytel, Dariusz, Mucha, Bartosz, Szymanek, Katarzyna, Szaflik, Jerzy, Szaflik, Jacek P., Majsterek, Ireneusz
Publicado no Biomed Res Int (2015)

Analysis of the Expression and Polymorphism of APOE, HSP, BDNF, and GRIN2B Genes Associated with the Neurodegeneration Process in the Pathogenesis of Primary Open Angle Glaucoma

Por Nowak, Alicja, Majsterek, Ireneusz, Przybyłowska-Sygut, Karolina, Pytel, Dariusz, Szymanek, Katarzyna, Szaflik, Jerzy, Szaflik, Jacek P.
Publicado no Biomed Res Int (2015)

PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

Por Bobrovnikova-Marjon, Ekaterina, Grigoriadou, Christina, Pytel, Dariusz, Zhang, Fang, Ye, Jiangbin, Koumenis, Constantinos, Cavener, Douglas, Diehl, J. Alan
Publicado em 2010

BCR/ABL stimulates WRN to promote survival and genomic instability

Por Slupianek, Artur, Poplawski, Tomasz, Jozwiakowski, Stanislaw K., Cramer, Kimberly, Pytel, Dariusz, Stoczynska, Ewelina, Nowicki, Michal O., Blasiak, Janusz, Skorski, Tomasz
Publicado em 2010

The Essential Oils of Rhaponticum carthamoides Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities

Por Skała, Ewa, Rijo, Patrícia, Garcia, Catarina, Sitarek, Przemysław, Kalemba, Danuta, Toma, Monika, Szemraj, Janusz, Pytel, Dariusz, Wysokińska, Halina, Śliwiński, Tomasz
Publicado no Oxid Med Cell Longev (2016)

PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Por Bobrovnikova-Marjon, Ekaterina, Pytel, Dariusz, Riese, Matthew J., Vaites, Laura Pontano, Singh, Nickpreet, Koretzky, Gary A., Witze, Eric S., Diehl, J. Alan
Publicado em 2012

Enzymatic Characterization of ER Stress-Dependent Kinase, PERK, and Development of a High-Throughput Assay for Identification of PERK Inhibitors

Por Pytel, Dariusz, Seyb, Kathleen, Liu, Min, Ray, Soumya S., Concannon, John, Huang, Mickey, Cuny, Gregory D., Diehl, J. Alan, Glicksman, Marcie A.
Publicado no J Biomol Screen (2014)

BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability

Por Slupianek, Artur, Falinski, Rafal, Znojek, Pawel, Stoklosa, Tomasz, Flis, Sylwia, Doneddu, Valentina, Pytel, Dariusz, Synowiec, Ewelina, Blasiak, Janusz, Bellacosa, Alfonso, Skorski, Tomasz
Publicado em 2012

Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Compositio...

Por Sitarek, Przemysław, Rijo, Patricia, Garcia, Catarina, Skała, Ewa, Kalemba, Danuta, Białas, Adam J., Szemraj, Janusz, Pytel, Dariusz, Toma, Monika, Wysokińska, Halina, Śliwiński, Tomasz
Publicado no Oxid Med Cell Longev (2017)

The ζ Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling

Por Joshi, Rohan P., Schmidt, Amanda M., Das, Jayajit, Pytel, Dariusz, Riese, Matthew J., Lester, Melissa, Diehl, J. Alan, Behrens, Edward M., Kambayashi, Taku, Koretzky, Gary A.
Publicado em 2013

miR-211 is a pro-survival micro-RNA that regulates chop expression in a PERK-dependent manner

Por Chitnis, Nilesh, Pytel, Dariusz, Bobrovnikova-Marjon, Ekaterina, Pant, Dhruv, Zheng, Hui, Maas, Nancy, Frederick, Brian, Kushner, Jake A., Chodosh, Lewis A., Koumenis, Constantinos, Fuchs, Serge Y., Diehl, J. Alan
Publicado em 2012

The FBXO4 Tumor Suppressor Functions as a Barrier to Braf(V600E)-Dependent Metastatic Melanoma

Por Lee, Eric K., Lian, Zhaorui, D'Andrea, Kurt, Letrero, Richard, Sheng, WeiQi, Liu, Shujing, Diehl, J. Nathaniel, Pytel, Dariusz, Barbash, Olena, Schuchter, Lynn, Amaravaradi, Ravi, Xu, Xiaowei, Herlyn, Meenhard, Nathanson, Katherine L., Diehl, J. Alan
Publicado em 2013

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma

Por Pytel, Dariusz, Gao, Yan, Mackiewicz, Katarzyna, Katlinskaya, Yuliya V., Staschke, Kirk A., Paredes, Maria C. G., Yoshida, Akihiro, Qie, Shuo, Zhang, Gao, Chajewski, Olga S., Wu, Lawrence, Majsterek, Ireneusz, Herlyn, Meenhard, Fuchs, Serge Y., Diehl, J. Alan
Publicado no PLoS Genet (2016)