The role of aging upon β cell turnover

Por Kushner, Jake A.
Publicado em 2013

Esophageal Stem Cells, Where Art Thou?: Are there stem cells in the esophagus or not?

Por Kushner, Jake A.
Publicado em 2012

Cellular Origins of Beta Cell Regeneration: a Legacy view of Historical Controversies

Por Granger, Anne, Kushner, Jake A.
Publicado em 2009

Adaptive β-Cell Proliferation Is Severely Restricted With Advanced Age

Por Rankin, Matthew M., Kushner, Jake A.
Publicado em 2009

Aging induces a distinct gene expression program in mouse islets

Por Rankin, Matthew M, Kushner, Jake A
Publicado em 2010

β-Cell Mass and Type 1 Diabetes: Going, Going, Gone?

Por Akirav, Eitan, Kushner, Jake A., Herold, Kevan C.
Publicado em 2008

Ductal origin hypothesis of pancreatic regeneration under attack

Por Kushner, Jake A., Weir, Gordon C., Bonner-Weir, Susan
Publicado em 2010

Prediction and Prevention of Type 1 Diabetes: Update on Success of Prediction and Struggles at Prevention

Por Michels, Aaron, Zhang, Li, Khadra, Anmar, Kushner, Jake A., Redondo, Maria J., Pietropaolo, Massimo
Publicado no Pediatr Diabetes (2015)

Dysregulation of insulin receptor substrate 2 in β cells and brain causes obesity and diabetes

Por Lin, Xueying, Taguchi, Akiko, Park, Sunmin, Kushner, Jake A., Li, Fan, Li, Yedan, White, Morris F.
Publicado em 2004

β-Cells Are Not Generated in Pancreatic Duct Ligation–Induced Injury in Adult Mice

Por Rankin, Matthew M., Wilbur, Christopher J., Rak, Kimberly, Shields, Emily J., Granger, Anne, Kushner, Jake A.
Publicado em 2013

Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice

Por Cox, Aaron R., Lam, Carol J., Bonnyman, Claire W., Chavez, Julia, Rios, Jacqueline S., Kushner, Jake A.
Publicado no Diabetologia (2015)

PERK Is Required in the Adult Pancreas and Is Essential for Maintenance of Glucose Homeostasis

Por Gao, Yan, Sartori, Daniel J., Li, Changhong, Yu, Qian-Chun, Kushner, Jake A., Simon, M. Celeste, Diehl, J. Alan
Publicado em 2012

Identification of a WD40 Repeat-Containing Isoform of PHIP as a Novel Regulator of β-Cell Growth and Survival

Por Podcheko, Alexey, Northcott, Paul, Bikopoulos, George, Lee, Andrew, Bommareddi, Swaroop R., Kushner, Jake A., Farhang-Fallah, Janet, Rozakis-Adcock, Maria
Publicado em 2007

Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth

Por Kushner, Jake A., Ciemerych, Maria A., Sicinska, Ewa, Wartschow, Lynn M., Teta, Monica, Long, Simon Y., Sicinski, Piotr, White, Morris F.
Publicado em 2005

Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU

Por Kiel, Mark J., He, Shenghui, Ashkenazi, Rina, Gentry, Sara N., Teta, Monica, Kushner, Jake A., Jackson, Trachette L., Morrison, Sean J.
Publicado em 2007

Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes

Por Shields, Emily J., Lam, Carol J., Cox, Aaron R., Rankin, Matthew M., Van Winkle, Thomas J., Hess, Rebecka S., Kushner, Jake A.
Publicado no PLoS One (2015)

Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage

Por Cox, Aaron R., Lam, Carol J., Rankin, Matthew M., King, Kourtney A., Chen, Pan, Martinez, Ramon, Li, Changhong, Kushner, Jake A.
Publicado no Diabetologia (2016)

Insulin-Like Growth Factor 2 and the Insulin Receptor, But Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis

Por Liang, Li, Guo, Wei Hui, Esquiliano, Diego R., Asai, Masato, Rodriguez, Susana, Giraud, Jodel, Kushner, Jake A., White, Morris F., Lopez, Mary Frances
Publicado em 2010

Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice: Control of Islet Vasculature and Vascular Endothelial Growth Factor by Glucose

Por Akirav, Eitan M., Baquero, Maria-Teresa, Opare-Addo, Lynn W., Akirav, Michael, Galvan, Eva, Kushner, Jake A., Rimm, David L., Herold, Kevan C.
Publicado em 2011

Cyclin D2 Protein Stability Is Regulated in Pancreatic β-Cells

Por He, Lu Mei, Sartori, Daniel J., Teta, Monica, Opare-Addo, Lynn M., Rankin, Matthew M., Long, Simon Y., Diehl, J. Alan, Kushner, Jake A.
Publicado em 2009