Insulin-Like Growth Factor 2 and the Insulin Receptor, But Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis

Whether insulin or IGFs regulate glycogen synthesis in the fetal liver remains to be determined. In this study, we used several knockout mouse strains, including those lacking Pdx-1 (pancreatic duodenal homeobox-1), Insr (insulin receptor), and Igf2 (IGF-II) to determine the role of these genes in t...

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Bibliographic Details
Main Authors: Liang, Li, Guo, Wei Hui, Esquiliano, Diego R., Asai, Masato, Rodriguez, Susana, Giraud, Jodel, Kushner, Jake A., White, Morris F., Lopez, Mary Frances
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817628/
https://ncbi.nlm.nih.gov/pubmed/20032056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0705
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