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Insulin-Like Growth Factor 2 and the Insulin Receptor, But Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis

Whether insulin or IGFs regulate glycogen synthesis in the fetal liver remains to be determined. In this study, we used several knockout mouse strains, including those lacking Pdx-1 (pancreatic duodenal homeobox-1), Insr (insulin receptor), and Igf2 (IGF-II) to determine the role of these genes in t...

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Detalhes bibliográficos
Main Authors: Liang, Li, Guo, Wei Hui, Esquiliano, Diego R., Asai, Masato, Rodriguez, Susana, Giraud, Jodel, Kushner, Jake A., White, Morris F., Lopez, Mary Frances
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817628/
https://ncbi.nlm.nih.gov/pubmed/20032056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0705
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