Insulin-Like Growth Factor 2 and the Insulin Receptor, But Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis

Whether insulin or IGFs regulate glycogen synthesis in the fetal liver remains to be determined. In this study, we used several knockout mouse strains, including those lacking Pdx-1 (pancreatic duodenal homeobox-1), Insr (insulin receptor), and Igf2 (IGF-II) to determine the role of these genes in t...

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Autores principales: Liang, Li, Guo, Wei Hui, Esquiliano, Diego R., Asai, Masato, Rodriguez, Susana, Giraud, Jodel, Kushner, Jake A., White, Morris F., Lopez, Mary Frances
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817628/
https://ncbi.nlm.nih.gov/pubmed/20032056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0705
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