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Insulin-Like Growth Factor 2 and the Insulin Receptor, But Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis

Whether insulin or IGFs regulate glycogen synthesis in the fetal liver remains to be determined. In this study, we used several knockout mouse strains, including those lacking Pdx-1 (pancreatic duodenal homeobox-1), Insr (insulin receptor), and Igf2 (IGF-II) to determine the role of these genes in t...

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Bibliografiske detaljer
Main Authors: Liang, Li, Guo, Wei Hui, Esquiliano, Diego R., Asai, Masato, Rodriguez, Susana, Giraud, Jodel, Kushner, Jake A., White, Morris F., Lopez, Mary Frances
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817628/
https://ncbi.nlm.nih.gov/pubmed/20032056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0705
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