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Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU

Stem cells are proposed to segregate chromosomes asymmetrically during self-renewing divisions so that older (‘immortal’) DNA strands are retained in daughter stem cells whereas newly synthesized strands segregate to differentiating cells1–6. Stem cells are also proposed to retain DNA labels, such a...

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Dettagli Bibliografici
Autori principali: Kiel, Mark J., He, Shenghui, Ashkenazi, Rina, Gentry, Sara N., Teta, Monica, Kushner, Jake A., Jackson, Trachette L., Morrison, Sean J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633872/
https://ncbi.nlm.nih.gov/pubmed/17728714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06115
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