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Analysis of the Expression and Polymorphism of APOE, HSP, BDNF, and GRIN2B Genes Associated with the Neurodegeneration Process in the Pathogenesis of Primary Open Angle Glaucoma

Glaucoma is characterized by optic neuropathy of the RGC or retinal nerve fiber. The aim of this study was to evaluate a relationship between the neurodegenerative genes' polymorphisms of the APOE (rs449647), BDNF (rs2030324), GRIN2B (rs3764028), and HSP70-1 (rs1043618) and the occurrence risk...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Nowak, Alicja, Majsterek, Ireneusz, Przybyłowska-Sygut, Karolina, Pytel, Dariusz, Szymanek, Katarzyna, Szaflik, Jerzy, Szaflik, Jacek P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393917/
https://ncbi.nlm.nih.gov/pubmed/25893192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/258281
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