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PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
In order to proliferate and expand in an environment with limited nutrients, cancer cells co-opt cellular regulatory pathways that facilitate adaptation and thereby maintain tumor growth and survival potential. The endoplasmic reticulum (ER) is uniquely positioned to sense nutrient deprivation stres...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900533/ https://ncbi.nlm.nih.gov/pubmed/20453876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.153 |
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