Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma

le Barone, Tara A, Burkhart, Catherine A, Safina, Alfiya, Haderski, Gary, Gurova, Katerina V, Purmal, Andrei A, Gudkov, Andrei V, Plunkett, Robert J
Foilsithe in Neuro Oncol (2017)

Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer

le Narizhneva, Natalia V., Tararova, Natalia D., Ryabokon, Petro, Shyshynova, Inna, Prokvolit, Anatoly, Komarov, Pavel G., Purmal, Andrei A., Gudkov, Andrei V., Gurova, Katerina V.
Foilsithe 2009

Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models

le Dermawan, Josephine Kam Tai, Hitomi, Masahiro, Silver, Daniel J., Wu, Qiulian, Sandlesh, Poorva, Sloan, Andrew E., Purmal, Andrei A., Gurova, Katerina V., Rich, Jeremy N., Lathia, Justin D., Stark, George R., Venere, Monica
Foilsithe in Cancer Res (2016)

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates

le Krivokrysenko, Vadim I., Toshkov, Ilia A., Gleiberman, Anatoli S., Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K., Narizhneva, Natalya V., Singh, Vijay K., Whitnall, Mark H., Purmal, Andrei A., Shakhov, Alexander N., Gudkov, Andrei V., Feinstein, Elena
Foilsithe in PLoS One (2015)

A deimmunized and pharmacologically optimized Toll-like receptor 5 agonist for therapeutic applications

le Mett, Vadim, Kurnasov, Oleg V., Bespalov, Ivan A., Molodtsov, Ivan, Brackett, Craig M., Burdelya, Lyudmila G., Purmal, Andrei A., Gleiberman, Anatoli S., Toshkov, Ilia A., Burkhart, Catherine A., Kogan, Yakov N., Andrianova, Ekaterina L., Gudkov, Andrei V., Osterman, Andrei L.
Foilsithe in Commun Biol (2021)

Curaxins: Anticancer Compounds that Simultaneously Suppress NF-κB and Activate p53 by Targeting FACT

le Gasparian, Alexander V., Burkhart, Catherine A., Purmal, Andrei A., Brodsky, Leonid, Pal, Mahadeb, Saranadasa, Madhi, Bosykh, Dmitry A., Commane, Mairead, Guryanova, Olga A., Pal, Srabani, Safina, Alfiya, Sviridov, Sergey, Koman, Igor E., Veith, Jean, Komar, Anton A., Gudkov, Andrei V., Gurova, Katerina V.
Foilsithe in Sci Transl Med (2011)