Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel

Por Sun, Liang, Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Ojima, Iwao
Publicado em 2010

Use of an Anti-Vascular Endothelial Growth Factor Antibody in a Pharmacokinetic Strategy to Increase the Efficacy of Intraperitoneal Chemotherapy

Por Shah, Dhaval K., Shin, Beom Soo, Veith, Jean, Tóth, Karoly, Bernacki, Ralph J., Balthasar, Joseph P.
Publicado em 2009

Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8(+) T-cell axis

Por Brackett, Craig M., Kojouharov, Bojidar, Veith, Jean, Greene, Kellee F., Burdelya, Lyudmila G., Gollnick, Sandra O., Abrams, Scott I., Gudkov, Andrei V.
Publicado no Proc Natl Acad Sci U S A (2016)

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice

Por Kojouharov, Bojidar M., Brackett, Craig M., Veith, Jean M., Johnson, Christopher P., Gitlin, Ilya I., Toshkov, Ilia A., Gleiberman, Anatoli S., Gudkov, Andrei V., Burdelya, Lyudmila G.
Publicado em 2014

Design, Synthesis and Biological Evaluation of Novel C14-C3’BzN–Linked Macrocyclic Taxoids

Por Sun, Liang, Geng, Xudong, Geney, Raphaël, Li, Yuan, Li, Zhong, Lauher, Joseph W., Xia, Shujun, Horwitz, Susan B., Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Ojima, Iwao
Publicado em 2008

Synthesis and Biological Evaluation of Novel 3′-Difluorovinyl Taxoids

Por Kuznetsova, Larissa, Sun, Liang, Chen, Jin, Zhao, Xianrui, Seitz, Joshua, Das, Manisha, Li, Yuan, Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Xia, Shujun, Horwitz, Susan B., Ojima, Iwao
Publicado em 2012

Design, Synthesis and Biological Evaluation of New Generation Taxoids

Por Ojima, Iwao, Chen, Jin, Sun, Liang, Borella, Christopher P., Wang, Tao, Miller, Michael L., Lin, Songnian, Geng, Xudong, Kuznetsova, Larisa, Qu, Chuanxing, Gallager, David, Zhao, Xianrui, Zanardi, Ilaria, Xia, Shujun, Horwitz, Susan B., Clair, Jon Mallen-St., Guerriero, Jennifer L., Bar-Sagi, Dafna, Veith, Jean M., Pera, Paula, Bernacki, Ralph J.
Publicado em 2008

Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist

Por Burdelya, Lyudmila G., Brackett, Craig M., Kojouharov, Bojidar, Gitlin, Ilya I., Leonova, Katerina I., Gleiberman, Anatoli S., Aygun-Sunar, Semra, Veith, Jean, Johnson, Christopher, Haderski, Gary J., Stanhope-Baker, Patricia, Allamaneni, Shyam, Skitzki, Joseph, Zeng, Ming, Martsen, Elena, Medvedev, Alexander, Scheblyakov, Dmitry, Artemicheva, Nataliya M., Logunov, Denis Y., Gintsburg, Alexander L., Naroditsky, Boris S., Makarov, Sergei S., Gudkov, Andrei V.
Publicado em 2013