Polyploidization and cancer

Por Poon, Randy Y.C.
Publicado em 2010

Aurora B: Hooking up with cyclin-dependent kinases

Por Poon, Randy Y.C.
Publicado em 2013

Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation

Por Woo, Richard A., Poon, Randy Y.C.
Publicado em 2004

Dovitinib induces mitotic defects and activates the G(2) DNA damage checkpoint

Por Man, Wing Yu, Mak, Joyce PY, Poon, Randy YC
Publicado em 2014

Specialized Roles of the Two Mitotic Cyclins in Somatic Cells: Cyclin A as an Activator of M Phase–promoting Factor

Por Fung, Tsz Kan, Ma, Hoi Tang, Poon, Randy Y.C.
Publicado em 2007

Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15‐dependent drug resistance

Por Ma, Hoi Tang, Erdal, Sergio, Huang, Shan, Poon, Randy Y.C.
Publicado no Mol Oncol (2014)

An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells

Por Ma, Hoi Tang, On, Kin Fan, Tsang, Yiu Huen, Poon, Randy Y.C.
Publicado em 2007

The requirement of p53 for maintaining chromosomal stability during tetraploidization

Por Ho, Chui Chui, Hau, Pok Man, Marxer, Miriam, Poon, Randy Y.C.
Publicado em 2010

SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A–B56

Por Wong, Wing Ki, Kelly, Terrenz, Li, Jingjing, Ma, Hoi Tang, Poon, Randy YC
Publicado no Cell Cycle (2015)

DNA Damage Mediated S and G(2) Checkpoints in Human Embryonal Carcinoma Cells

Por Wang, XiaoQi, Lui, Vincent CH, Poon, Ronnie TP, Lu, Ping, Poon, Randy YC
Publicado em 2009

Pharmacological targeting the ATR–CHK1–WEE1 axis involves balancing cell growth stimulation and apoptosis

Por Mak, Joyce P.Y., Man, Wing Yu, Ma, Hoi Tang, Poon, Randy Y.C.
Publicado no Oncotarget (2014)

P21 and Retinoblastoma Protein Control the Absence of DNA Replication in Terminally Differentiated Muscle Cells

Por Mal, Asoke, Chattopadhyay, Debasis, Ghosh, Mrinal K., Poon, Randy Y.C., Hunter, Tony, Harter, Marian L.
Publicado em 2000

CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency

Por Wang, Xiao Qi, Lo, Chung Mau, Chen, Lin, Ngan, Elly S-W, Xu, Aimin, Poon, Randy YC
Publicado no Cell Death Differ (2017)

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells

Por Mak, Joyce P.Y., Man, Wing Yu, Chow, Jeremy P.H., Ma, Hoi Tang, Poon, Randy Y.C.
Publicado no Oncotarget (2015)

Conditional gene inactivation by combining tetracycline-mediated transcriptional repression and auxin-inducible degron-mediated degradation

Por Ng, Lau Yan, Ma, Hoi Tang, Liu, Julio C.Y., Huang, Xiner, Lee, Nelson, Poon, Randy Y.C.
Publicado no Cell Cycle (2019)

G1 checkpoint establishment in vivo during embryonic liver development

Por Wang, Xiao Qi, Chan, Kwok Kin, Ming, Xiaoyan, Lui, Vincent CH, Poon, Randy YC, Lo, Chung Mau, Norbury, Chris, Poon, Ronnie TP
Publicado em 2014

Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe

Por Li, Jingjing, Hong, Myung Jin, Chow, Jeremy P.H., Man, Wing Yu, Mak, Joyce P.Y., Ma, Hoi Tang, Poon, Randy Y.C.
Publicado no Oncotarget (2015)

DNA Damage during the Spindle-Assembly Checkpoint Degrades CDC25A, Inhibits Cyclin–CDC2 Complexes, and Reverses Cells to Interphase

Por Chow, Jeremy P.H., Siu, Wai Yi, Fung, Tsz Kan, Chan, Wan Mui, Lau, Anita, Arooz, Talha, Ng, Chuen-Pei, Yamashita, Katsumi, Poon, Randy Y.C.
Publicado em 2003

Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells

Por Xia, Wei, Lo, Chung Mau, Poon, Randy Y.C., Cheung, Tan To, Chan, Albert C.Y., Chen, Lin, Yang, Sitian, Tsao, George S.W., Wang, Xiao Qi
Publicado no Oncotarget (2017)

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis

Por Ye, Fei, Kang, Eunchai, Yu, Chuan, Qian, Xuyu, Jacob, Fadi, Yu, Cong, Mao, Mao, Poon, Randy Y.C., Kim, Jieun, Song, Hongjun, Ming, Guo-li, Zhang, Mingjie
Publicado no Neuron (2017)