Finding New Collaboration Models for Enabling Neglected Tropical Disease Drug Discovery

af Pollastri, Michael P.
Udgivet 2014

Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon

af Pollastri, Michael P.
Udgivet i Trends Parasitol (2017)

The importance of collaboration between industry, academics, and non-profits in tropical disease drug discovery.

af Ferrins, Lori, Pollastri, Michael P.
Udgivet i ACS Infect Dis (2017)

Target repurposing for neglected diseases

af Pollastri, Michael P, Campbell, Robert K
Udgivet 2011

REPURPOSING STRATEGIES FOR TROPICAL DISEASE DRUG DISCOVERY

af Klug, Dana M., Gelb, Michael H., Pollastri, Michael P.
Udgivet i Bioorg Med Chem Lett (2016)

The challenge of developing robust drugs to overcome resistance

af Anderson, Amy C., Schiffer, Celia, Pollastri, Michael, Peet, Norton P.
Udgivet 2011

Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis

af Thomas, Sarah M., Purmal, Andrei, Pollastri, Michael, Mensa-Wilmot, Kojo
Udgivet i Sci Rep (2016)

Erratum: Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis

af Thomas, Sarah M., Purmal, Andrei, Pollastri, Michael, Mensa-Wilmot, Kojo
Udgivet i Sci Rep (2017)

Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

af Amata, Emanuele, Bland, Nicholas D., Campbell, Robert K., Pollastri, Michael P.
Udgivet i Tetrahedron Lett (2015)

Novel Effects of Lapatinib Revealed in the African Trypanosome by Using Hypothesis-Generating Proteomics and Chemical Biology Strategies

af Guyett, Paul J., Behera, Ranjan, Ogata, Yuko, Pollastri, Michael, Mensa-Wilmot, Kojo
Udgivet i Antimicrob Agents Chemother (2017)

Identification and characterization of Kava-derived compounds mediating TNF-α suppression

af Pollastri, Michael P., Whitty, Adrian, Merrill, Jamie Cassidy, Ashton, Trent D., Amar, Salomon
Udgivet 2009

Kinases as Druggable Targets in Trypanosomatid Protozoan Parasites

af Merritt, Christopher, Silva, Lisseth E., Tanner, Angela L., Stuart, Kenneth, Pollastri, Michael P.
Udgivet i Chem Rev (2014)

Glycogen Synthase Kinase 3β Promotes the Endocytosis of Transferrin in the African Trypanosome

af Guyett, Paul J., Xia, Shuangluo, Swinney, David C., Pollastri, Michael, Mensa-Wilmot, Kojo
Udgivet i ACS Infect Dis (2016)

Optimization of Physicochemical Properties for 4-Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation

af Mehta, Naimee, Ferrins, Lori, Leed, Susan E., Sciotti, Richard J., Pollastri, Michael P.
Udgivet i ACS Infect Dis (2018)

Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei

af Ochiana, Stefan O., Bland, Nicholas D., Settimo, Luca, Campbell, Robert K., Pollastri, Michael P.
Udgivet i Chem Biol Drug Des (2014)

Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

af Woodring, Jennifer L., Bland, Nicholas D., Ochiana, Stefan O., Campbell, Robert K., Pollastri, Michael P.
Udgivet 2013

Repurposing human PDE4 inhibitors for neglected tropical diseases: Design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors

af Amata, Emanuele, Bland, Nicholas D., Hoyt, Charles T., Settimo, Luca, Campbell, Robert K., Pollastri, Michael P.
Udgivet 2014

The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

af Ochiana, Stefan O., Pandarinath, Vidya, Wang, Zhouxi, Kapoor, Rishika, Ondrechen, Mary Jo, Ruben, Larry, Pollastri, Michael P.
Udgivet 2012

A Chemical Screen Identifies Small Molecules that Regulate Hepcidin Expression

af Gaun, Vera, Patchen, Bonnie, Volovetz, Josephine, Zhen, Aileen W., Andreev, Aleksandr, Pollastri, Michael P., Fraenkel, Paula G.
Udgivet 2014

Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum

af Absalon, Sabrina, Blomqvist, Karin, Rudlaff, Rachel M., DeLano, Travis J., Pollastri, Michael P., Dvorin, Jeffrey D.
Udgivet i mBio (2018)