Target repurposing for neglected diseases

von Pollastri, Michael P, Campbell, Robert K
Veröffentlicht 2011

Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

von Amata, Emanuele, Bland, Nicholas D., Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht in Tetrahedron Lett (2015)

Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei

von Ochiana, Stefan O., Bland, Nicholas D., Settimo, Luca, Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht in Chem Biol Drug Des (2014)

Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

von Woodring, Jennifer L., Bland, Nicholas D., Ochiana, Stefan O., Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht 2013

Repurposing human PDE4 inhibitors for neglected tropical diseases: Design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors

von Amata, Emanuele, Bland, Nicholas D., Hoyt, Charles T., Settimo, Luca, Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht 2014

Threading of a glycosylated protein loop through a protein hole: Implications for combination of human chorionic gonadotropin subunits

von Xing, Yongna, Williams, Christopher, Campbell, Robert K., Cook, Stephanie, Knoppers, Maria, Addona, Theresa, Altarocca, Valter, Moyle, William R.
Veröffentlicht 2001

Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. 2. Tadalafil analogs

von Ochiana, Stefan O., Gustafson, Alden, Bland, Nicholas, Wang, Cuihua, Russo, Michael J., Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht 2012

Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. 1. Sildenafil analogs

von Wang, Cuihua, Ashton, Trent D., Gustafson, Alden, Bland, Nicholas D., Ochiana, Stefan O., Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht 2012

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases B1 and B2 as Druggable Targets for African Sleeping Sickness

von Bland, Nicholas D., Wang, Cuihua, Tallman, Craig, Gustafson, Alden E., Wang, Zhouxi, Ashton, Trent D., Ochiana, Stefan O., McAllister, Gregory, Cotter, Kristina, Fang, Anna P., Gechijian, Lara, Garceau, Norman, Gangurde, Rajiv, Ortenberg, Ron, Ondrechen, Mary Jo, Campbell, Robert K., Pollastri, Michael P.
Veröffentlicht 2011

Genomic-scale prioritization of drug targets: the TDR Targets database

von Agüero, Fernán, Al-Lazikani, Bissan, Aslett, Martin, Berriman, Matthew, Buckner, Frederick S., Campbell, Robert K., Carmona, Santiago, Carruthers, Ian M., Chan, A. W. Edith, Chen, Feng, Crowther, Gregory J., Doyle, Maria A., Hertz-Fowler, Christiane, Hopkins, Andrew L., McAllister, Gregg, Nwaka, Solomon, Overington, John P., Pain, Arnab, Paolini, Gaia V., Pieper, Ursula, Ralph, Stuart A., Riechers, Aaron, Roos, David S., Sali, Andrej, Shanmugam, Dhanasekaran, Suzuki, Takashi, Voorhis, Wesley C. Van, Verlinde, Christophe L. M. J.
Veröffentlicht 2008