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Identification and characterization of Kava-derived compounds mediating TNF-α suppression

There is a substantial unmet need for new classes of drugs that block TNF-α-mediated inflammation, and particularly for small molecule agents that can be taken orally. We have screened a library of natural products against an assay measuring TNF-α secretion in lipopolysaccharide (LPS)-stimulated THP...

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Hlavní autoři: Pollastri, Michael P., Whitty, Adrian, Merrill, Jamie Cassidy, Ashton, Trent D., Amar, Salomon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754715/
https://ncbi.nlm.nih.gov/pubmed/19538508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00838.x
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