Suppression of endothelial cell activity by inhibition of TNFα

INTRODUCTION: TNFα is a proinflammatory cytokine that plays a central role in the pathogenesis of rheumatoid arthritis (RA). We investigated the effects of certolizumab pegol, a TNFα blocker, on endothelial cell function and angiogenesis. METHODS: Human dermal microvascular endothelial cells (HMVECs...

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Detalhes bibliográficos
Main Authors: Shu, Qiang, Amin, Mohammad A, Ruth, Jeffrey H, Campbell, Phillip L, Koch, Alisa E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446462/
https://ncbi.nlm.nih.gov/pubmed/22534470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3812
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