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Glycogen Synthase Kinase 3β Promotes the Endocytosis of Transferrin in the African Trypanosome

Human parasite Trypanosoma brucei proliferates in the blood of its host, where it takes up iron via receptor-mediated endocytosis of transferrin (Tf). Mechanisms of Tf endocytosis in the trypanosome are not fully understood. Small molecule lapatinib inhibits Tf endocytosis in T. brucei and associate...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Guyett, Paul J., Xia, Shuangluo, Swinney, David C., Pollastri, Michael, Mensa-Wilmot, Kojo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025259/
https://ncbi.nlm.nih.gov/pubmed/27626104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00077
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