Disease implications of the Hippo/YAP pathway

Por Plouffe, Steven W, Hong, Audrey W, Guan, Kun-Liang
Publicado no Trends Mol Med (2015)

A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids

Por Xu, Liang, Plouffe, Steven W., Chong, Jenny, Wengel, Jesper, Wang, Dong
Publicado em 2013

Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis

Por Xu, Liang, Da, Lintai, Plouffe, Steven W., Chong, Jenny, Kool, Eric, Wang, Dong
Publicado em 2014

The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1

Por Hansen, Carsten Gram, Ng, Yuen Lam Dora, Lam, Wai-Ling Macrina, Plouffe, Steven W, Guan, Kun-Liang
Publicado no Cell Res (2015)

Characterization of Hippo pathway components by gene inactivation

Por Plouffe, Steven W., Meng, Zhipeng, Lin, Kimberly C., Lin, Brian, Hong, Audrey W., Chun, Justin V., Guan, Kun-Liang
Publicado no Mol Cell (2016)

Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation

Por Gong, Rui, Hong, Audrey W, Plouffe, Steven W, Zhao, Bin, Liu, Guangbo, Yu, Fa-Xing, Xu, Yanhui, Guan, Kun-Liang
Publicado no Cell Res (2015)

Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

Por Hong, Audrey W, Meng, Zhipeng, Yuan, Hai‐Xin, Plouffe, Steven W, Moon, Sungho, Kim, Wantae, Jho, Eek‐hoon, Guan, Kun‐Liang
Publicado no EMBO Rep (2016)

Differential regulation of mTORC1 by leucine and glutamine

Por Jewell, Jenna L., Kim, Young Chul, Russell, Ryan C., Yu, Fa-Xing, Park, Hyun Woo, Plouffe, Steven W., Tagliabracci, Vincent S., Guan, Kun-Liang
Publicado no Science (2015)

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

Por Moroishi, Toshiro, Park, Hyun Woo, Qin, Baodong, Chen, Qian, Meng, Zhipeng, Plouffe, Steven W., Taniguchi, Koji, Yu, Fa-Xing, Karin, Michael, Pan, Duojia, Guan, Kun-Liang
Publicado no Genes Dev (2015)

Alternative Wnt Signaling Activates YAP/TAZ

Por Park, Hyun Woo, Kim, Young Chul, Yu, Bo, Moroishi, Toshiro, Mo, Jung-Soon, Plouffe, Steven W., Meng, Zhipeng, Lin, Kimberly C., Yu, Fa-Xing, Alexander, Caroline M., Wang, Cunyu, Guan, Kun-Liang
Publicado no Cell (2015)

Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

Por Meng, Fansen, Zhou, Ruyuan, Wu, Shiying, Zhang, Qian, Jin, Qiuheng, Zhou, Yao, Plouffe, Steven W., Liu, Shengduo, Song, Hai, Xia, Zongping, Zhao, Bin, Ye, Sheng, Feng, Xin-Hua, Guan, Kun-Liang, Zou, Jian, Xu, Pinglong
Publicado no Genes Dev (2016)

Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

Por Zhang, Qian, Meng, Fansen, Chen, Shasha, Plouffe, Steven W., Wu, Shiying, Liu, Shengduo, Li, Xinran, Zhou, Ruyuan, Wang, Junxian, Zhao, Bin, Liu, Jianming, Qin, Jun, Zou, Jian, Feng, Xin-Hua, Guan, Kun-Liang, Xu, Pinglong
Publicado no Nat Cell Biol (2017)

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Por Meng, Zhipeng, Moroishi, Toshiro, Mottier-Pavie, Violaine, Plouffe, Steven W., Hansen, Carsten G., Hong, Audrey W., Park, Hyun Woo, Mo, Jung-Soon, Lu, Wenqi, Lu, Shicong, Flores, Fabian, Yu, Fa-Xing, Halder, Georg, Guan, Kun-Liang
Publicado no Nat Commun (2015)