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Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

YAP is the major downstream effector of the Hippo pathway, which controls cell growth, tissue homeostasis, and organ size. Aberrant YAP activation, resulting from dysregulation of the Hippo pathway, is frequently observed in human cancers. YAP is a transcription co‐activator, and the key mechanism o...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Hong, Audrey W, Meng, Zhipeng, Yuan, Hai‐Xin, Plouffe, Steven W, Moon, Sungho, Kim, Wantae, Jho, Eek‐hoon, Guan, Kun‐Liang
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210094/
https://ncbi.nlm.nih.gov/pubmed/27979971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642681
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