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Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP
YAP is the major downstream effector of the Hippo pathway, which controls cell growth, tissue homeostasis, and organ size. Aberrant YAP activation, resulting from dysregulation of the Hippo pathway, is frequently observed in human cancers. YAP is a transcription co‐activator, and the key mechanism o...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5210094/ https://ncbi.nlm.nih.gov/pubmed/27979971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642681 |
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