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NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition
The mechanistic target of rapamycin (mTOR) is a central cell growth controller and forms two distinct complexes: mTORC1 and mTORC2. mTORC1 integrates a wide range of upstream signals, both positive and negative, to regulate cell growth. Although mTORC1 activation by positive signals, such as growth...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691891/ https://ncbi.nlm.nih.gov/pubmed/26588989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265116.115 |
| Oznake: |
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