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Micro(RNA) Managing by mTORC1

In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.

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Bibliographic Details
Published in:Mol Cell
Main Authors: Jewell, Jenna L., Flores, Fabian, Guan, Kun-Liang
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378617/
https://ncbi.nlm.nih.gov/pubmed/25699705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.006
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