Phosphorylation by NLK inhibits YAP‐14‐3‐3‐interactions and induces its nuclear localization

Hippo signaling controls organ size by regulating cell proliferation and apoptosis. Yes‐associated protein (YAP) is a key downstream effector of Hippo signaling, and LATS‐mediated phosphorylation of YAP at Ser127 inhibits its nuclear localization and transcriptional activity. Here, we report that Ne...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Moon, Sungho, Kim, Wantae, Kim, Soyoung, Kim, Youngeun, Song, Yonghee, Bilousov, Oleksii, Kim, Jiyoung, Lee, Taebok, Cha, Boksik, Kim, Minseong, Kim, Hanjun, Katanaev, Vladimir L, Jho, Eek‐hoon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210122/
https://ncbi.nlm.nih.gov/pubmed/27979972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642683
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