MAML1/2 promote YAP/TAZ nuclear localization and tumorigenesis

The Hippo pathway plays a pivotal role in tissue homeostasis and tumor suppression. YAP and TAZ are downstream effectors of the Hippo pathway, and their activities are tightly suppressed by phosphorylation-dependent cytoplasmic retention. However, the molecular mechanisms governing YAP/TAZ nuclear l...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kim, Jiyoung, Kwon, Hyeryun, Shin, You Keun, Song, Gahyeon, Lee, Taebok, Kim, Youngeun, Jeong, Wonyoung, Lee, Ukjin, Zhang, Xianglan, Nam, Gilyeong, Jeung, Hei-Cheul, Kim, Wantae, Jho, Eek-hoon
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306791/
https://ncbi.nlm.nih.gov/pubmed/32482852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917969117
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker