Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

The Hippo pathway senses cellular conditions and regulates YAP/TAZ to control cellular and tissue homeostasis, while TBK1 is central for cytosolic nucleic acid sensing and antiviral defense. The correlation between cellular nutrient/physical status and host antiviral defense is interesting but not w...

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Veröffentlicht in:Nat Cell Biol
Hauptverfasser: Zhang, Qian, Meng, Fansen, Chen, Shasha, Plouffe, Steven W., Wu, Shiying, Liu, Shengduo, Li, Xinran, Zhou, Ruyuan, Wang, Junxian, Zhao, Bin, Liu, Jianming, Qin, Jun, Zou, Jian, Feng, Xin-Hua, Guan, Kun-Liang, Xu, Pinglong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398908/
https://ncbi.nlm.nih.gov/pubmed/28346439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3496
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